A list of citations to recent publications from our scientific advisory board
Dr. Gordon Amidon
- Incecayir, Tuba, et al. "Carrier-Mediated Prodrug Uptake to Improve the Oral Bioavailability of Polar Drugs: An Application to an Oseltamivir Analogue."Journal of pharmaceutical sciences 105.2 (2016): 925-934.
- Cao, Fengjuan, et al. "Mechanistic Analysis of Cocrystal Dissolution as a Function of pH and Micellar Solubilization." Molecular pharmaceutics 13.3 (2016): 1030-1046.
- Talattof, Arjang, Judy C. Price, and Gordon L. Amidon. "Gastrointestinal Motility Variation and Implications for Plasma Level Variation: Oral Drug Products." Molecular pharmaceutics 13.2 (2016): 557-567.
- Matsui, Kazuki, et al. "The Evaluation of In Vitro Drug Dissolution of Commercially Available Oral Dosage Forms for Itraconazole in Gastrointestinal Simulator With Biorelevant Media." Journal of pharmaceutical sciences (2016).
- Sheng, Jennifer J., and Gordon L. Amidon. "8 The Biopharmaceutics Classification System: Recent Applications in Pharmaceutical Discovery, Development, and Regulation." Oral Drug Absorption (2016): 138.
Dr. Marival Bermejo
- Casañola-Martin, Gerardo, et al. "Exploring different strategies for imbalanced ADME data problem: case study on Caco-2 permeability modeling." Molecular diversity 20.1 (2016): 93-109.
Dr. Jack A. Cook
- Younis, Islam R., et al. "Utility of Model Based Approaches for Informing Dosing Recommendations in Specific Populations: Report from the Public AAPS Workshop." The Journal of Clinical Pharmacology (2016).
Dr. Peter Langgut
- Brüll, Verena, et al. "Acute intake of quercetin from onion skin extract does not influence postprandial blood pressure and endothelial function in overweight-to-obese adults with hypertension: a randomized, double-blind, placebo-controlled, crossover trial." European journal of nutrition (2016): 1-11.
- Kranz, Lena M., et al. "Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy." Nature (2016).
- Jabulowsky, Robert A., et al. "Abstract B041: A novel nanoparticular formulated tetravalent RNA cancer vaccine for treatment of patients with malignant melanoma." Cancer Immunology Research 4.1 Supplement (2016): B041-B041.
- Knopp, Matthias Manne, et al. "Influence of polymer molecular weight on in vitro dissolution behavior and in vivo performance of celecoxib: PVP amorphous solid dispersions." European Journal of Pharmaceutics and Biopharmaceutics 101 (2016): 145-151.
- Knopp, Matthias Manne, et al. "Influence of Copolymer Composition on In Vitro and In Vivo Performance of Celecoxib-PVP/VA Amorphous Solid Dispersions." The AAPS journal 18.2 (2016): 416-423.
- Knopp, Matthias Manne, et al. "Effect of polymer type and drug dose on the in vitro and in vivo behavior of amorphous solid dispersions." European Journal of Pharmaceutics and Biopharmaceutics (2016).
- Knopp, Matthias Manne, et al. "A promising new method to estimate drug-polymer solubility at room temperature." Journal of pharmaceutical sciences (2016).
- Goodarzi, Navid, et al. "Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Ribavirin." Journal of pharmaceutical sciences 105.4 (2016): 1362-1369.
- Al-Gousous, Jozef, and Peter Langguth. "Effect of Calcium Ions on the Disintegration of Enteric-Coated Solid Dosage Forms." Journal of pharmaceutical sciences 105.2 (2016): 509-511.
- Gogoll, Karsten, et al. "Solid Nanoemulsion as Antigen and Immunopotentiator Carrier for Transcutaneous Immunization." Cellular Immunology (2016).
Dr. Hans Lennernä
- Johannsson, Gudmundur, et al. "Achieving a physiological cortisol profile with once-daily dual-release hydrocortisone: a pharmacokinetic study." European Journal of Endocrinology 175.1 (2016): 85-93.
Dr. James Poll
- Li, Qing, et al. "Effect of Ondansetron on Metformin Pharmacokinetics and Response in Healthy Subjects." Drug Metabolism and Disposition 44.4 (2016): 489-494.
- Ting, Tricia, et al. "Evaluation of Reproducibility of Pharmacokinetics and Clinical Outcome Differences with Brand and Generic Lamotrigine Switching in Epilepsy Patients (BEEP FU Study)(P2. 033)." Neurology 86.16 Supplement (2016): P2-033.
- Vaithianathan, Soundarya, et al. "Effect of common excipients on the oral drug absorption of biopharmaceutics classification system class 3 drugs cimetidine and acyclovir." Journal of pharmaceutical sciences 105.2 (2016): 996-1005.
- Vaithianathan, Soundarya, et al. "Reply to “On the Effect of Common Excipients on the Oral Absorption of Class 3 Drugs”." Journal of pharmaceutical sciences 105.4 (2016): 1355-1357.
- Goodarzi, Navid, et al. "Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Ribavirin." Journal of pharmaceutical sciences 105.4 (2016): 1362-1369.
- Stack, Christopher, James Polli, and Tricia Ting. "Pill Color Preference Considerations in Clinical Trial Design (P2. 037)." Neurology 86.16 Supplement (2016): P2-037.
- Vaithianathan, Soundarya, et al. "Release of levetiracetam from extended-release tablets that appear intact in patient stool." Seizure 40 (2016): 7-9.
- Polli, James E. "11 BCS: Today and Tomorrow." Oral Drug Absorption(2016): 206.
Dr. Ikumi Tama
- Incecayir, Tuba, et al. "Carrier-Mediated Prodrug Uptake to Improve the Oral Bioavailability of Polar Drugs: An Application to an Oseltamivir Analogue."Journal of pharmaceutical sciences 105.2 (2016): 925-934.
- Takeuchi, Ryota, et al. "Local Drug–Drug Interaction of Donepezil with Cilostazol at Breast Cancer Resistance Protein (ABCG2) Increases Drug Accumulation in Heart." Drug Metabolism and Disposition 44.1 (2016): 68-74.
- Kasai, Taku, et al. "Role of OATP2A1 in PGE 2 secretion from human colorectal cancer cells via exocytosis in response to oxidative stress."Experimental cell research 341.2 (2016): 123-131.
- Fujita, Daichi, et al. "Organic anion transporting polypeptide (OATP) 2B1 contributes to gastrointestinal toxicity of anticancer drug SN-38, active metabolite of irinotecan hydrochloride." Drug Metabolism and Disposition44.1 (2016): 1-7.
- Hoshino, Yusuke, et al. "Molecular localization and characterization of multiple binding sites of organic anion transporting polypeptide 2B1 (OATP2B1) as the mechanism for substrate and modulator dependent drug-drug interaction." MedChemComm (2016).
- Gose, Tomoka, et al. "Prostaglandin transporter (OATP2A1/SLCO2A1) contributes to local disposition of eicosapentaenoic acid-derived PGE 3."Prostaglandins & other lipid mediators 122 (2016): 10-17.
- Matsunaga, Norikazu, et al. "Analysis of the metabolic pathway of bosentan and of the cytotoxicity of bosentan metabolites based on a quantitative modeling of metabolism and transport in sandwich-cultured human hepatocytes." Drug Metabolism and Disposition 44.1 (2016): 16-27.
- Saito, Yoshimasa, et al. "A retrospective study of treatment and prophylaxis of ifosfamide-induced hemorrhagic cystitis in pediatric and adolescent and young adult (AYA) patients with solid tumors." Japanese Journal of Clinical Oncology (2016).
Dr. Shinji Yamashit
- Hisada, Nozomi, et al. "Characterizing the Dissolution Profiles of Supersaturable Salts, Cocrystals, and Solvates to Enhance In Vivo Oral Absorption." European Journal of Pharmaceutics and Biopharmaceutics(2016).
- Nagai, Mika, et al. "Establishment of in silico prediction models for CYP3A4 and CYP2B6 induction in human hepatocytes by multiple regression analysis using azole compounds." Drug Metabolism and Disposition (2016): dmd-115.
- Kataoka, Makoto, et al. "Effects of gastric pH on oral drug absorption: In vitro assessment using a dissolution/permeation system reflecting the gastric dissolution process." European Journal of Pharmaceutics and Biopharmaceutics 101 (2016): 103-111.
- Kovacevic, Goran, and Shinji Yamashita. "Waveguide design parameters impact on absorption in graphene coated silicon photonic integrated circuits."Optics express 24.4 (2016): 3584-3591.
- Higashino, Haruki, et al. "Effect of precipitation/re-dissolution processes from the supersaturated solution on the intestinal absorption of poorly water-soluble drugs." asian journal of pharmaceutical sciences 11.1 (2016): 68-69.
- Yano, Koji, et al. "Evaluation of dose-dependent oral absorption of a newly developed drug candidate: In vitro-in vivo correlation." Journal of Drug Delivery Science and Technology 31 (2016): 160-166.
- Miyaji, Yoshihiro, et al. "Advantage of the Dissolution/Permeation system for estimating oral absorption of drug candidates in the drug discovery stage."Molecular pharmaceutics 13.5 (2016): 1564-1574.
- Yoshimatsu, Hiromichi, et al. "Usefulness of minipigs for predicting human pharmacokinetics: Prediction of distribution volume and plasma clearance."Drug metabolism and pharmacokinetics 31.1 (2016): 73-81.